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Fosamax Mar 26

    Client Attorney Privileged/Attorney Work Product/At Request of Counsel

  1. Bone Drug--Another Wonder Drug That Wasn't

    Mar 23, 2015 | OpEd News

    By Martha Rosenberg

    ... Bisphosphonates like Fosamax and Boniva (the latter, advertised by actress Sally Field) were quickly substituted as a way for women to keep their bones strong and stay young looking. But soon they r evealed risks of their own. In addition to intractable pain, atrial fibrillation...

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    Client Attorney Privileged/Attorney Work Product/At Request of Counsel

  1. Bone Drug--Another Wonder Drug That Wasn't

    Mar 23, 2015 | OpEd News

    By Martha Rosenberg

    Monkeys developed tooth and jaw abscesses and two died of protozoal infections. Human subjects developed cervical, ovarian, pancreatic, gastric and thyroid cancers and breast cancer " was the most common adverse event that led to discontinuation" in trials. Adverse event?

    Ten people were hospitalized with the skin infection cellulitis during trials and one died.

    ...The bone drug market opened up for the drug industry 12 years ago when the hormone replacement drugs women were taking to prevent fractures were found to increase their risks of cancer and heart disease. Bisphosphonates like Fosamax and Boniva (the latter, advertised by actress Sally Field) were quickly substituted as a way for women to keep their bones strong and stay young looking. But soon they revealed risks of their own. In addition to intractable pain, atrial fibrillation and causing (not preventing) atypical fractures, bisphosphonates were linked to jaw bone death (osteonecrosis) and esophageal cancer.

    Soon Prolia began to appear no safer than the bisophosphonates though it belonged to a different class of drugs. A monoclonal antibody derived from genetically engineered Chinese hamster ovary cells, Prolia carries warnings like other "MoAbs" about opportunistic infections, anaphylaxis and worse...

    For full story:

    http://www.opednews.com/articles/Bone-Drug-Another-Wonder-by-Martha-Rosenberg-Aging_Aging-Anti-aging-Longevity_Antiaging_Drug-Companies-Marketing-150325-408.html

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